10 min read·Apr 18, 2026
Tirzepatide vs Semaglutide: What the 2025 SURMOUNT-5 Trial Actually Tells Us
The SURMOUNT-5 head-to-head trial showed tirzepatide achieved 20.2% weight loss vs 13.7% for semaglutide over 72 weeks. Here's what the data means — and what it doesn't.
TirzepatideSemaglutide